Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7868720 | Materials Science and Engineering: C | 2015 | 8 Pages |
Abstract
A sensitive electrochemical sensor has been fabricated to detect Isoniazid (INZ) using reduced graphene oxide (RGO) and Au nanocomposites (RGO-Au). RGO-Au nanocomposites were synthesized by a solution-based approach of chemical co-reduction of Au(III) and graphene oxide (GO), and were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Raman spectroscopy, and Fourier transform infrared (FT-IR). The Au nanoparticles separate the RGO sheets in the precipitate and prevent RGO sheets from aggregation upon Ï-Ï stacking interactions. RGO-Au nanocomposites were used to modify the glassy carbon electrode (GCE). The electrochemical properties of RGO-Au/GCE were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), and the RGO-Au/GCE exhibited remarkably strong electrocatalytic activities towards INZ. Under the optimized conditions, there was linear relationships between the peak currents and the concentrations in the range of 1.0 Ã 10â 7 M to 1.0 Ã 10â 3 M for INZ, with the limit of detection (LOD) (based on S/N = 3) of 1.0 Ã 10â 8 M for INZ.
Related Topics
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Authors
Zhuo Guo, Ze-yu Wang, Hui-hua Wang, Guo-qing Huang, Meng-meng Li,