Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7869523 | Materials Science and Engineering: C | 2015 | 9 Pages |
Abstract
We optimized methods for the isolation of primary endothelial cells from mouse liver. Applying this optimized methodology, the molecular response of liver sinusoidal endothelial cells on hydrogels was evaluated. Interestingly, PEG-based hydrogels strongly affected the molecular response of endothelial cells and induced cellular stress reflected by significant alterations in endothelial cell adhesion molecule marker expression.
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Matthias Bartneck, Fuat Topuz, Carmen Gabriele Tag, Sibille Sauer-Lehnen, Klaudia Theresa Warzecha, Christian Trautwein, Ralf Weiskirchen, Frank Tacke,