Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7886049 | Ceramics International | 2018 | 15 Pages |
Abstract
Poor bio-corrosion resistance and undesirable incomplete osseointegration restrict the application of hydroxyapatite (HA) as an implant coating material. In this study, a novel F-and-La co-substituted hydroxyapatite (FLaHA) coating, which was reinforced with strontium titanate nanotubes (STNTs), was applied on Ti substrates using a combination method of anodization, electrochemical deposition and hydrothermal treatment. To the best of our knowledge, this is the first report on the development of FLaHA/STNT coatings for improving the chemical stability and the mechanical and biological properties of Ti substrates. The STNT exhibits an evenly-distributed porous and latticed structure on Ti substrates that favours the infiltration of FLaHA crystals. Different characterisation techniques, such as x-ray photoemission spectroscopy, x-ray diffraction, field-emission scanning electron microscopy and energy-dispersive spectroscopy, have clearly confirmed the successful synthesis of STNT-FLaHA coatings that constitute oriented nanorod arrays. Isolated hexagonal nanorod grains, with diameters of 200-300â¯nm, that stand on a substrate provide a uniform morphology to the surface of electrodeposited thin films at micro-scales. The survival of the coatings was prolonged because of their good degradation resistance. Owing to the anchoring effect of the STNT layer, the adhesion strength of the FLaHA/STNT coating was 15.9â¯Â±â¯5.4â¯MPa, which was two times higher than that of STNT-free HA coatings. The potentiodynamic polarisation curves and the Nyquist plot confirmed that the conversion coating significantly improved the bio-corrosion resistance of the Ti substrates in the SBF solution. Roughness and hydrophilicity of the control HA layer were even greater than those of the FLaHA/STNT coating. However, it provided better cell adhesion, spreading, proliferation and osteogenic differentiation for mouse pre-osteoblasts cells. That is, the FLaHA/STNT coating could enhance osteoconductivity by improving the cell-adhesion, proliferation and differentiation of osteoblast. Therefore, FLaHA/STNT nanocomposite coatings can be used as implant materials with multi-functional properties, such as good biocompatibility and high mechanical and corrosion-inhibiting properties.
Related Topics
Physical Sciences and Engineering
Materials Science
Ceramics and Composites
Authors
Haixia Qiao, Qingshuang Zou, Cuifang Yuan, Xuejiao Zhang, Shuguang Han, Zhenhui Wang, Xiaopei Bu, Hui Tang, Yong Huang,