| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7925086 | Optics Communications | 2018 | 4 Pages |
Abstract
Here we report and review the investigation of bone microenvironment in vivo with harmonic generation microscopy. Excited by an infrared femtosecond laser, the second harmonic generation images can reveal the bone structures and boundaries. The third harmonic generation images can reveal the osteocytes, connecting canaliculi, and granular bone marrow cells. These imaging features can be used to observe and analyze the histology of the bone microenvironment in the future.
Related Topics
Physical Sciences and Engineering
Materials Science
Electronic, Optical and Magnetic Materials
Authors
Pei-Chun Wu, Yu-Fang Shen, Chi-Kuang Sun, Charles P. Lin, Tzu-Ming Liu,