Article ID Journal Published Year Pages File Type
801037 Mechanics Research Communications 2009 10 Pages PDF
Abstract

The purpose of this research is to improve a semi-mechanistic bone remodeling theory. In addition to entering the cellular accommodation effect into the model, a novel unifying formulation to include the effects of both microdamage and disuse on activation of resorption as the first phase of remodeling was introduced. Using the modified model, trabecular-like structures for different loading conditions and directionalities similar to actual human trabecular bone have been resulted. This research also shows that including cellular accommodation and simultaneous effects of microdamage and disuse will help to predict more realistic morphologies in time-dependent simulations.

Related Topics
Physical Sciences and Engineering Engineering Mechanical Engineering
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