Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8012647 | Materials Letters | 2018 | 12 Pages |
Abstract
A novel guided tissue regeneration (GTR) membrane with orthogonal aligned fibers in surface layers and random fibers within interlayer was developed by multilayer electrospinning. The mechanical strength of tri-layer membrane was between random and aligned membranes. The promotion of the proliferations of MC3T3-E1 and NIH-3â¯T3 cells on the tri-layer membrane were observed during monoculture. When cells were cocultured, the tri-layer membrane was effective in impeding MC3T3-E1 and NIH-3â¯T3 cell infiltration by guiding cells to grow along the direction of the fiber alignment.
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Authors
Yao Ge, Rui-peng Chen, Hong Li, Zhen-zhao Guo,