| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8015513 | Materials Letters | 2018 | 4 Pages |
Abstract
Octacalcium phosphate (OCP) foam with an interconnected porous structure was fabricated through phase conversion via a dissolution-precipitation reaction using calcium sulfate hemihydrate (CSH: CaSO4·1/2H2O) granules as precursors in a sodium dihydrogen phosphate (NaDP: NaH2PO4) solution. The diametral tensile strength and porosity of the OCP foam were 0.15â¯Â±â¯0.04â¯MPa and 69.4%â¯Â±â¯0.04%, respectively. When the OCP foam was implanted into bone defects in a rabbit femur, the OCP foam showed an excellent tissue response, and the bone penetrated into the porous structure. The osteoconductivity and bone-replacement rate were significantly higher than those of an OCP compact.
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Authors
Yuki Sugiura, Melvin L. Munar, Kunio Ishikawa,