Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8016372 | Materials Letters | 2016 | 11 Pages |
Abstract
Nanofibrous tubular poly(L-lactic acid) (PLLA) scaffolds were fabricated by centrifugation combined with thermally induced phase separation technique using PLLA/1,4-dioxane/water ternary system, at input voltage of 4.00 V and phase separation temperature of â15 °C. Addition of sucrose led to the generation of porous scaffolds with interconnected pores. Input voltage was the crucial factor to generate nanofibrous tubular scaffold that mimicked the structural features of the biological systems. The surface of nanofibrous tubular scaffold provided a good environment for attachment and proliferation of MC3T3-E1 subclone 14 cells, exhibiting significant potential for bone tissue regeneration.
Related Topics
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Authors
Shunyu Chen, Zhihang He, Guojie Xu, Xiufeng Xiao,