The effect of magnesium alloy wires and tricalcium phosphate particles on apatite mineralization on polylactide-based composites

Biodegradable magnesium alloy wires and tricalcium phosphate nanoparticles were used as a modifying phase of novel polylactide based composite system. The aim of this study was to determine the effect of those two components on apatite mineralization and thus potential bioactivity of the composite material. Studied samples were incubated in Simulated Body Fluid and Phosphate Buffer Saline to simulate biological environment. It was revealed that coexisting modification of polymer matrix with Mg and TCP resulted in formation of apatites with magnesium substitutions that have superior biological properties. Results of the study confirmed that chemical composition of the incubation medium affects composition of the precipitates. Designed multiphase composite can be potentially used for bioactive bone implants.