| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8016972 | Materials Letters | 2016 | 4 Pages |
Abstract
Multi-layered biodegradable membranes (MLMs) were fabricated by combining electrospinning and solvent casting/particulate leaching methods. MLMs possess three layers of different functional properties; poly (caprolactone) (PCL)/nano-hydroxyapatite core layer and PCL/collagen, PCL/collagen-bone morphogenic protein 7 (BMP 7) outer layers on each side of the core layer. MC3T3-E1 cell culture tests showed that osteoblastic differentiation was enhanced on PCL/collagen BMP 7 layer. This facile method presents great potential for fabrication of multi-functional barrier membranes for periodontal regeneration as well as scaffolds possessing different properties to mimic complex extra cellular matrix structures with stable integrity.
Related Topics
Physical Sciences and Engineering
Materials Science
Nanotechnology
Authors
Sühan Gürbüz, T. Tolga DemirtaÅ, Emre Yüksel, AyÅe Karakeçili, Altan DoÄan, MenemÅe GümüÅderelioÄlu,