Polymer coatings for biomedical applications using atmospheric pressure plasma

For this study, the organic coatings included biocompatible polymers such as poly(2-hydroxyethylmethacrylate), polyethylenimine, and polyethylene glycol. Atmospheric pressure plasma was used, along with an in-house constructed spray delivery system, to graft the molecules to HMWPE substrates. The surface of the substrates was maintained at a temperature below 80 °C during the coating process. Coatings were characterized by Fourier transform infrared spectroscopy (FTIR), contact angle analysis, and adhesion testing. A significant decrease in contact angle was noted for various coatings produced with this method, indicating increased hydrophilicity. Plasma processing conditions, specifically the pretreatment of the substrate and the input power, affected the adhesion and uniformity of the polymerized layer. Trends varied for the polymers used in this study, indicating the need for optimization of plasma parameters for the desired polymer coating.