| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8054462 | Applied Mathematics Letters | 2015 | 7 Pages |
Abstract
In this paper, a delay differential equation model of immunotherapy for tumor-immune response is presented. The dynamics that interplays between the three model factors, namely, effector cells, tumor cells and interleukin-2 is studied and the quantitative analysis is performed. We estimate the length of delay to preserve the stability of an equilibrium state of biological significance. The impact of delay in the immunotherapy with interleukin-2, especially, at different antigenicity levels, is discussed, along with the scenarios under which the tumor remission can be prolonged.
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Authors
Sandip Banerjee, Alexei Tsygvintsev,