| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 810554 | Journal of the Mechanical Behavior of Biomedical Materials | 2015 | 6 Pages |
Abstract
Biodegradable and star-shaped polymers with highly tunable structure and properties have attracted much attention in recent years for potential biomedical applications, due to their special structure. Here, inositol-based star-shaped poly-l-lactide-poly(ethylene glycol) (INO-PLLA-PEG) biomedical polymer implants were for the first time synthesized by a facile photo-crosslinking method. This biomaterials show controlled elastomeric mechanical properties (~18 MPa in tensile strength, ~200 MPa in modulus, ~200% in elongation), biodegradability and osteoblasts biocompatibility. These results make INO-PLLA-PEG implants highly promising for bone tissue regeneration and drug delivery applications.
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Meihua Xie, Juan Ge, Yumeng Xue, Yuzhang Du, Bo Lei, Peter X Ma,