Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8131054 | Ultrasound in Medicine & Biology | 2018 | 11 Pages |
Abstract
A high-frequency scanning system consisting of a 20-MHz linear array transducer combined with a 20-MHz pulsed Doppler probe was introduced to evaluate the degree of radial artery flow-mediated dilation (FMD [%]) in two groups of patients after 5âmin of controlled forearm ischemia followed by reactive hyperemia. In group I, comprising 27 healthy volunteers, FMD (meanâ±âstandard deviation) was 15.26â±â4.90% (95% confidence interval [CI]: 13.32%-17.20%); in group II, comprising 17 patients with chronic coronary artery disease, FMD was significantly less at 4.53â±â4.11% (95% CI: 2.42%-6.64%). Specifically, the ratio FMD/SR (meanâ±âstandard deviation), was equal to 5.36âÃâ10â4â±â4.64âÃâ10â4 (95% CI: 3.54âÃâ10â4 to 7.18âÃâ10â4) in group I and 1.38âÃâ10â4â±â0.89âÃâ10â4 (95% CI: 0.70âÃâ10â4 to 2.06âÃâ10â4) in group II. Statistically significant differences between the two groups were confirmed by a Wilcoxon-Mann-Whitney test for both FMD and FMD/SR (pâ<0.01). Areas under receiver operating characteristic curves for FMD and FMD/SR were greater than 0.9. The results confirm the usefulness of the proposed measurements of radial artery FMD and SR in differentiation of normal patients from those with chronic coronary artery disease.
Keywords
Related Topics
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Physics and Astronomy
Acoustics and Ultrasonics
Authors
Andrzej Nowicki, Zbigniew Trawinski, Barbara Gambin, Wojciech Secomski, MichaÅ Szubielski, Marzena Parol, Robert Olszewski,