Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8131092 | Ultrasound in Medicine & Biology | 2018 | 5 Pages |
Abstract
The purpose of this study was to validate the feasibility of contrast-enhanced transcranial Doppler sonography (CE-TCCD) in the diagnosis of Moyamoya disease (MMD). CE-TCCD data on patients with MMD were analyzed. The CE-TCCD data were classified qualitatively into four patterns by two independent investigators: normal vascular color Doppler signal (pattern 1), augmented color Doppler signal with identifiable vascular structure (pattern 2), confluent color Doppler signal filling more than two-thirds of the display frame without identifiable vascular structure (pattern 3) and confluent color Doppler signal filling full display (pattern 4). To investigate the validity, we compared the CE-TCCD data with traditional transcranial Doppler data and Suzuki grades on cerebral angiography. A total of 32 CE-TCCD studies from 16 MMD patients (male 37.5%, median age 48) were included in this study. The CE-TCCD findings were distributed across patterns 1 (nâ=â3), 2 (nâ=â12), 3 (nâ=â10) and 4 (nâ=â7) and were correlated with the Suzuki grades (pâ<0.005) and hemodynamic parameters. Inter-rater reliability was promising (Cronbach αâ=â0.883). The CE-TCCD test provides distinctive patterns in MMD, according to their stage of progression. CE-TCCD patterns seem to be a reliable and valid means for the evaluation of MMD.
Related Topics
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Acoustics and Ultrasonics
Authors
Woo-Keun Seo, Chang-Woon Choi, Chi Kyung Kim, Kyungmi Oh,