Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8131362 | Ultrasound in Medicine & Biology | 2018 | 10 Pages |
Abstract
The aim of this study was to assess the normal ranges of liver stiffness measurements (LSMs) in participants with healthy livers, using General Electric 2-D shear wave elastography (2-D-SWE-GE) compared with transient elastography (TE). We included 80 participants with healthy livers and without known liver disease, in whom liver stiffness was evaluated in the same session using two elastographic methods, TE and 2-D-SWE-GE. Reliable LSMs were defined for TE as the median of 10 measurements with a success rate of â¥60% and an interquartile range (IQR)â<â30%, and for 2-D-SWE-GE, as the median of 10 measurements acquired in a homogenous area and an IQRâ<â30%. Participants with LSMsâ>â6.5âkPa by TE were excluded. Reliable LSMs were obtained in 79 participants (98.7%) by means of 2-D-SWE-GE and in 80 participants (100%) by means of TE (pâ=â0.9). The mean LSM obtained by 2-D-SWE-GE in our cohort of participants with healthy livers was 5.1â±â1.3âkPa, which was significantly higher than the LSM assessed by TE (4.3â±â0.9âkPa, pâ<â0.0001). In 2-D SWE-GE, mean LSMs were significantly higher for men than for women, 5.9â±â1.2âkPa versus 4.7â±â1.2âkPa (pâ=â0.0005). In conclusion, 2-D-SWE-GE has very good feasibility (98.7%) in healthy persons. The mean LSM determined by 2-D-SWE-GE in healthy participants was 5.1â±â1.3âkPa. LSMs obtained by means of 2-D-SWE-GE were higher than those obtained by TE in participants with healthy livers.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Acoustics and Ultrasonics
Authors
Felix Bende, Anesa Mulabecirovic, Ioan Sporea, Alina Popescu, Roxana Sirli, Odd Helge Gilja, Mette Vesterhus, Roald Flesland Havre,