Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8164045 | Physica C: Superconductivity and its Applications | 2018 | 16 Pages |
Abstract
Dextran-coated magnetite (Fe3O4) nanoparticles with average particle sizes of 4 and 19â¯nm were synthesized through in situ and semi-two-step co-precipitation methods, respectively. The experimental results confirm the formation of pure phase of magnetite as well as the presence of dextran layer on the surface of modified magnetite nanoparticles. The results also reveal that both samples have the superparamagnetic behavior. Furthermore, calorimetric measurements show that the dextran-coated Fe3O4 nanoparticles with an average size of 4â¯nm cannot produce any appreciable heat under a biologically safe alternating magnetic field used in hyperthermia therapy; whereas, the larger ones (average size of 19â¯nm) are able to increase the temperature of their surrounding medium up to above therapeutic range. In addition, measured specific absorption rate (SAR) values confirm that magnetite nanoparticles with an average size of 19â¯nm are very excellent candidates for application in magnetic hyperthermia therapy.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Zhila Shaterabadi, Gholamreza Nabiyouni, Meysam Soleymani,