Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
816576 | Beni-Suef University Journal of Basic and Applied Sciences | 2015 | 8 Pages |
Abstract
Novel series of dialkylaminoalkyl-o-cresols incorporated with purine nucleus 2a–b, benzothiazole nucleus 5a–b, 8a–b and thiazole nucleus 11a–d, 13a–d were synthesized through Mannich reaction. Structures of the newly synthesized compounds have been deduced on the basis of elemental analysis and spectral data. Antimicrobial activity evaluation was carried out for all synthesized compounds; most of them exerted comparable activity to ciprofloxacin and flucanazole. The thiazole derivatives 11a, 13c, 13d are the most potent compounds.
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Authors
Khaled R.A. Abdellatif, Ghada A. Abd El Wareth, Ossama M. El-Badry, Hamdy M. Ragab, Mervat M. El-Enany,