Article ID Journal Published Year Pages File Type
8166030 Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2018 31 Pages PDF
Abstract
Positron emission tomography (PET) is used to research high order functions in the brain. There is a lot of brain activity in the gray matter. To study the function of the corpus callosum in gray matter, a spatial resolution of approximately 1 mm is necessary. Using 640 two-dimensional position-sensitive cadmium tellurium (CdTe) detectors with a spatial full width half maximum (FWHM) resolution of 1 mm, we made a brain PET. Our aim was to obtain a resolution (FWHM) of 1 mm at a position 100 mm from the center of the gantry. Though the positions of the 640 detectors can be estimated based on the shape of the gantry, it is not easy to determine their exact positions. We developed a method to determine the detector position by analyzing the distribution of the lines-of-response (LORs) between two detector blocks. We obtained this distribution by measuring a sodium (22Na) point source with a diameter of 1 mm. We reconstructed images of the point source using the maximum likelihood-expectation maximization (ML-EM) method using the corrected positions of the detectors. We succeeded in achieving a resolution (FWHM) of 1.6 mm at a distance of 100 mm from the center of the gantry.
Related Topics
Physical Sciences and Engineering Physics and Astronomy Instrumentation
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