| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8180483 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | 2013 | 4 Pages |
Abstract
In this technological report, we investigate the utility of whole-body diffusion-weighted MRI (WBDWI) as a prior for defining regions of interest (ROI) in PET data. Due to its comparatively high resolution and excellent lesion-to-background ratio, semi-automatic segmentation is possible in WBDWI. Following rigid registration of PET to WBDWI, a simple, fast and automatic algorithm can be used to define ROIs in PET data. This approach is applied to a test cohort of patients diagnosed with lymphoma who underwent both 18FDG-PET/CT and WBDWI studies to demonstrate its potential application.
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Authors
M.D. Blackledge, D.M. Koh, D.J. Collins, S. Chua, M.O. Leach,