| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8208407 | Applied Radiation and Isotopes | 2018 | 5 Pages |
Abstract
We proposed use of astatine-210 in preclinical study. Astatine-210 has higher yield of production and is easier to quantify than astatine-211. We produced astatine-210 with Bi target and 40 MeV alpha beam accelerated by cyclotron, free astatine-210 was separated and injected to normal rats. Three male rats (blocking group) were injected non-radioactive iodide before injection of astatine-210. Compared with the control group, the astatine-210 accumulations in the blocking group decreased to 24% in the thyroid.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Hayato Ikeda, Yoshihiko Hayashi, Naruto Takahashi, Tadashi Watabe, Yasukazu Kanai, Atsushi Shinohara, Hiroki Kato, Hiroshi Watabe, Eku Shimosegawa, Jun Hatazawa,