Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8208841 | Applied Radiation and Isotopes | 2018 | 23 Pages |
Abstract
The γ-H2AX assay was investigated as an alternative to the time-consuming dicentric chromosome assay (DCA). Radiation doses to 25 radiotherapy patients were estimated in parallel by DCA and the γ-H2AX assay. The γ-H2AX assay yielded doses in line with the calculated equivalent whole body doses in 92% of the patients, whereas the success rate of DCA was only 76%. The result shows that the γ-H2AX assay can be effectively used as a rapid and more precise alternative to DCA.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Bhavani Manivannan, Thayalan Kuppusamy, Srinivasan Venkatesan, Venkatachalam Perumal,