| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8209581 | Applied Radiation and Isotopes | 2015 | 4 Pages |
Abstract
We evaluated DNA double-strand breaks (DSBs) induced by boron neutron capture reaction (BNCR) using plasmid DNA, boron solution, and gel electrophoresis. The amount of the linear form of DNA produced by DSBs increased with the neutron-beam irradiation dose. The amount of the open-circular form of DNA produced by single-strand breaks (SSBs) increased with the neutron-beam irradiation dose and the 10B concentration. The model facilitated quantification of BNCR-induced DSBs and SSBs, irrespective of the DNA repair mechanism.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Emiko Okamoto, Tetsuya Yamamoto, Kei Nakai, Fumiyo Yoshida Fumiyo Yoshida, Akira Matsumura,