Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8209608 | Applied Radiation and Isotopes | 2015 | 4 Pages |
Abstract
In this report the efficacy of extracellular pharmaceutical Gd-DTPA in Binary Radiotherapy was studied. The study was carried out in mice bearing transplantable adenocarcinoma Ca755 using X-ray based contrast enhanced radiotherapy as a practical implementation of Binary Radiotherapy. It was shown that intravenous administration of 0.3 ml of 0.5 M water solution of Gd-DTPA followed by X-irradiation at a dose of 10 Gy provides T/C%=10±3% and leads to complete tumor regression in 25% of mice.
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Authors
A.A. Lipengolts, A.A. Cherepanov, V.N. Kulakov, E.Yu. Grigorieva, I.N. Sheino, V.A. Klimanov,