Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8209721 | Applied Radiation and Isotopes | 2015 | 6 Pages |
Abstract
Interest in 68Ga has led to a number of innovations for its provision suitable for clinical application. Several post-processing methods are available to reduce eluate volume and remove metal trace impurities. In this work three cation exchange resin based post-processing methods (acetone, ethanol and NaCl) have been compared, using three model precursors (DOTATOC, NO2APBP and DATAm), in terms of labelling yield and reproducibility. The acetone and ethanol based methods provided greater reproducibility and yields that makes subsequent purification unnecessary.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Johanna Seemann, Elisabeth Eppard, Bradley P. Waldron, Tobias L. Ross, Frank Roesch,