| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8210123 | Applied Radiation and Isotopes | 2014 | 5 Pages |
Abstract
N-Succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) is a potential prosthetic agent for novel tracer development in positron emission tomography (PET). Previously, we reported a microwave-assisted one-pot synthesis of [18F]SFB with high efficacy. Herein, we reveal an improved and optimized approach based on this former model for producing [18F]SFB. With optimized approaches, the entire protocol can be completed within 25Â min, and [18F]SFB is generated in satisfactory quality for direct use without further purification via high-performance liquid chromatography.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
![Improved and optimized one-pot method for N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) synthesis using microwaves](/preview/png/8210123.png "First Page Preview: Improved and optimized one-pot method for N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) synthesis using microwaves")
Authors
Kang-Po Li, Ming-Kuan Hu, Clifton Kwang-Fu Shen, Wei-Yu Lin, Shuang Hou, Li-Bo Zhao, Cheng-Yi Cheng, Daniel. H. Shen,