| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8210373 | Applied Radiation and Isotopes | 2014 | 5 Pages |
Abstract
The principles of green chemistry have been applied to a radiochemistry setting. Eleven carbon-11 labeled radiopharmaceuticals have been prepared using ethanol as the only organic solvent throughout the entire manufacturing process. The removal of all other organic solvents from the process simplifies production and quality control (QC) testing, moving our PET Center towards the first example of a green radiochemistry laboratory. All radiopharmaceutical doses prepared are suitable for clinical use.
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Authors
Xia Shao, Maria V. Fawaz, Keunsam Jang, Peter J.H. Scott,