Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8210479 | Applied Radiation and Isotopes | 2014 | 8 Pages |
Abstract
Microfluidic systems are currently receiving a lot of attention in the PET radiochemistry field, due to their demonstrated ability to obtain higher incorporation yields with reduced total processing time and using a decreased amount of precursors. The Advion NanoTek LF was the first commercial microfluidic system available for radiochemistry that allows basic parameter optimization to be performed. In this paper we report hardware and software modifications that would allow better performing procedures, higher product throughput and flexibility to utilize the system. In particular, HPLC purification and SPE formulation have been fully integrated.
Keywords
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Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Giancarlo Pascali, Andrea Berton, Mariarosaria DeSimone, Naomi Wyatt, Lidia Matesic, Ivan Greguric, Piero A. Salvadori,