Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8210532 | Applied Radiation and Isotopes | 2013 | 6 Pages |
Abstract
Aim of this work was the implementation of a generalized in-loop synthesis for 11C-carboxylations and subsequent 11C-acylations on the TRACERlab FxC Pro platform. The set-up was tested using [carbonyl-11C]WAY-100635 and, for the first time, [11C]-(+)-PHNO. Its general applicability could be demonstrated and both [carbonyl-11C]WAY-100635 and [11C]-(+)-PHNO were prepared with high reliability and satisfying outcome.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Christina Rami-Mark, Johanna Ungersboeck, Daniela Haeusler, Lukas Nics, Cecile Philippe, Markus Mitterhauser, Matthaeus Willeit, Rupert Lanzenberger, Georgios Karanikas, Wolfgang Wadsak,