Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8210533 | Applied Radiation and Isotopes | 2013 | 5 Pages |
Abstract
A New 18F-Labeled Styryl Benzoxazole Derivative ([18F]-1) for β-Amyloid Targeting has been synthesized in good radiochemical yield and high radiochemical purity (>99%, both isomers. Biodistribution and metabolism studies of 18F]-1 in male Wistar rats have shown that this new radiotracer can cross the BBB but has a poor in vivo stability.
Related Topics
Physical Sciences and Engineering
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Radiation
Authors
G. Ribeiro Morais, L. Gano, T. Kniess, R. Bergmann, A. Abrunhosa, I. Santos, A. Paulo,