| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8210757 | International Journal of Radiation Oncology*Biology*Physics | 2018 | 9 Pages |
Abstract
High-precision heart irradiation with 8 and 16Â Gy using an 8Â ÃÂ 6-mm2 beam induced cardiac amyloidosis and hypertrophy, which did not lead to myocardial dysfunction despite the presence of radiation pneumopathy in the small V16 of the exposed lung. By using the improved irradiation plan (V16: 7%), long-term survival of the mice after heart irradiation can be achieved that allows clinically relevant experimental investigation of late radiation-induced heart disease effects.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Wolfgang PhD, Stefan PhD, Katja VMD, Gabriele PhD,