| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8210896 | International Journal of Radiation Oncology*Biology*Physics | 2018 | 38 Pages |
Abstract
Reactive oxygen species-induced NLRP3 inflammasomes mediated radiation-induced pyroptosis of the intestinal cells, and FlaAN/C suppressed pyroptosis to protect the intestinal tissue. These results provide novel insights into the mechanisms underlying radiation-induced cytotoxicity, and FlaAN/C might be a potential preventive therapy for radiation-induced intestinal injury in patients with cancer.
Related Topics
Physical Sciences and Engineering
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Authors
Dongming MS, Rong MS, Shihua MS, Teng BM, Ting MS, Hongxiang BM, Ying PhD,