Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8211024 | International Journal of Radiation Oncology*Biology*Physics | 2018 | 40 Pages |
Abstract
These data show for the first time that MSCs are resistant to IR and largely preserve their defining functions after irradiation irrespective of their tissue of origin. Efficient repair of IR-induced DNA double-strand breaks and consecutive reduction of apoptosis induction may contribute to the tissue-independent radiation resistance of MSCs.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Alexander Rühle, Oliver Xia, Ramon Lopez PhD, Thuy Trinh, Wiltrud PhD, Anna PhD, Patrick MD, Jürgen MD, PhD, Rainer PhD, Peter E. MD, PhD, Nils H. MD, PhD,