Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8211489 | International Journal of Radiation Oncology*Biology*Physics | 2018 | 12 Pages |
Abstract
These findings implicate ATIC as an effective, and previously unrecognized, target for chemoradiosensitization and, more broadly, suggest that purine levels in cells might have an underappreciated role in modulating the efficiency of DNA damage responses that could be exploited in radiosensitizing strategies.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Xiangfei PhD, Uma Devi PhD, Sharon N. PhD, Jocyndra A. Wright, Xin MS, Aaron R. PhD, Richard A. MD, Patrick PhD,