Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8211629 | International Journal of Radiation Oncology*Biology*Physics | 2017 | 9 Pages |
Abstract
This study verified the CRT-induced immunologic shift toward increases in PD-L1 expression and density of CD8+ TILs in rectal cancer patients. The alteration profiles of checkpoint-related molecules identified the patients with poor prognosis, suggesting potential candidates who can benefit from combining CRT and checkpoint inhibitors.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Yu Jin MD, Jaemoon MD, Sehui MD, Sang-Rok MS, Eui Kyu MD, PhD, Kyubo MD, PhD, Gyeong Hoon MD, PhD, Sae-Won MD, PhD, Tae-You MD, PhD, Seung-Yong MD, PhD, Kyu Joo MD, PhD, Hong-Gyun MD, PhD,