| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8211641 | International Journal of Radiation Oncology*Biology*Physics | 2017 | 20 Pages |
Abstract
Despite comparable IG-IMRT techniques and predefined dose constraints, pronounced differences in dose distributions and toxicity rates were observed. MRI delineation and ERB application were associated with favorable rectal dose parameters and toxicity profiles, whereas a 2- to 3-mm difference in PTV margins did not translate into observed differences. We conclude that choices for treatment optimization of IG-IMRT are important and clinically relevant for patients since these affect symptoms experienced in daily life.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Ruud C. MD, Wilma D. PhD, Robert Jan MD, PhD, Marnix G. PhD, Stijn D.G. MD, PhD, Floris J. MD, PhD, Luca MD, PhD,