| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8214560 | International Journal of Radiation Oncology*Biology*Physics | 2016 | 25 Pages |
Abstract
The present study suggests that the use of upfront EGFR-TKI, and the deferral of SRS or WBRT, may result in inferior OS in patients with EGFR-mutant NSCLC who develop brain metastases. A prospective, multi-institutional, randomized trial of upfront EGFR-TKI with RT at intracranial progression versus upfront RT followed by EGFR-TKI is urgently needed.
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Authors
William J. MD, Jacky T. MD, Paul D. BS, Scott N. MD, James B. MD, Veronica L. MD,