Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8214611 | International Journal of Radiation Oncology*Biology*Physics | 2016 | 10 Pages |
Abstract
Our data suggest that hypoxia potentiates the radiation-sensitizing effects of olaparib by contextual synthetic killing, and that tumor hypoxia may be a potential biomarker for selecting patients who may get the greatest benefit from the addition of olaparib to radiation therapy.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Yanyan PhD, Tom MSc, Aoife M. PhD, Sivan M. PhD, Anika M. PhD, Katarzyna B. PhD, Ester M. PhD, Anderson J. PhD,