| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8214620 | International Journal of Radiation Oncology*Biology*Physics | 2016 | 9 Pages |
Abstract
Radiation sensitization with Wee1 inhibition occurs in cells regardless of their p53 mutational status. In this study we show for the first time that replication stress via the overconsumption of nucleotides plays an important role in AZD1775-induced radiation sensitization.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Kyle C. MD, Meredith A. PhD, Mary A. PhD, Leslie A. PhD, Joshua BS, David PhD, Caila Ryan, Na BS, Jonathan PhD, Theodore S. MD, PhD,