Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8214849 | International Journal of Radiation Oncology*Biology*Physics | 2016 | 31 Pages |
Abstract
Supporting the favorable prognosis of HPV-positive HNSCCs, we show that (1) HPV-positive HNSCCs have a lower frequency of CSCs; (2) RT can dedifferentiate HNSCC cells into CSCs; and (3) radiation-induced dedifferentiation depends on the HPV status of the tumor.
Related Topics
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Radiation
Authors
Erina PhD, Allen M. MD, Sabrina MD, Garrett Yu, Andrea Nguyen, Philip A. Brower, Clayton B. MD, Frank MD, PhD,