Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8214956 | International Journal of Radiation Oncology*Biology*Physics | 2016 | 33 Pages |
Abstract
If either a fixed RBE of 1.1 or a variable RBE model could be validated in vivo, then it would always be possible to use AO IMPT to dose-boost the prostate and improve normal tissue sparing relative to IMRT. For a cohort without rectum spacer gels, this study (1) underlines the importance of resolving the question of proton RBE within the framework of an IMRT versus proton debate for the prostate and (2) highlights that without further LET/RBE model validation, great care must be taken if AO proton fields are to be considered for prostate treatments.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Tracy DPhil, Drosoula PhD, Maryam PhD, Anthony MD, Jason MD, DPhil, Harald PhD, Hsiao-Ming PhD,