Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8216409 | International Journal of Radiation Oncology*Biology*Physics | 2015 | 10 Pages |
Abstract
We suggest that simvastatin has a synergistic effect with radiation on GC and CRC through the induction of apoptosis, which may be mediated by a simultaneous inhibition of BIRC5 and CTGF expression. A clinical trial of simvastatin in combination with radiation in patients with GC or CRC is warranted.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Taekyu MD, PhD, Inkyoung Lee, Jungmin Kim, Won Ki MD, PhD,