| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8217346 | International Journal of Radiation Oncology*Biology*Physics | 2015 | 9 Pages |
Abstract
Our cell line screen has revealed variations in proton RBE that are partly due to FA/BRCA pathway defects, suggesting that the use of a generic RBE for cancers should be revisited. We propose that functional biomarkers, such as size of residual 53BP1 foci, may be used to identify cancers with increased sensitivity to proton radiation.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Qi PhD, Priyanjali BA, Nicole BS, Mauro PhD, Shikui PhD, Liliana MS, Peter PhD, Harald PhD, Jason A. MD, DPhil, Hsiao-Ming PhD, Kathryn D. PhD, Henning MD,