Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8217619 | International Journal of Radiation Oncology*Biology*Physics | 2015 | 10 Pages |
Abstract
The introduction of TC staining to the PCC fusion technique has made possible the rapid scoring of unstable CAs, including dicentrics, with a level of accuracy and ease not previously possible. This new approach can be used for biological dosimetry in radiation emergency medicine, where the rapid and accurate detection of dicentrics is a high priority using automated scoring. Because there is no culture time, this new approach can also be used for the follow-up of patients treated by genotoxic therapy, creating the possibility to perform the estimation of induced chromosomal aberrations immediately after the blood draw.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Radhia PhD, Elie PhD, Georgia PhD, Michelle PhD, Leonhard MS, Ionna PhD, Eric MS, William M. PhD, Bruno PhD, Alain PhD, Gabriel PhD, Laure PhD,