Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8219889 | International Journal of Radiation Oncology*Biology*Physics | 2014 | 6 Pages |
Abstract
Exposure of mice to neutrons generated by a proton dose that exceeds a typical course of radiation therapy by a factor of 10, resulted in a statistically significant increase in the background incidence of leukemia and a marginally significant increase in solid cancer. The results indicate that the risk of out-of-field second solid cancers from SOBP proton-generated neutrons and typical treatment schedules, is 6 to 10 times less than is suggested by current neutron risk estimates.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Leo E. PhD, Peigen MD, Hsiao-Ming PhD, Harald PhD, Yenong BS,