Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8220142 | International Journal of Radiation Oncology*Biology*Physics | 2014 | 7 Pages |
Abstract
Data presented here provide evidence that death at the LD50 in ferrets is most likely due to disseminated intravascular coagulation (DIC). These data question the current hypothesis that death at relatively low doses of radiation is due solely to the cell-killing effects of hematopoietic cells. The recognition that radiation-induced DIC is the most likely mechanism of death in ferrets raises the question of whether DIC is a contributing mechanism to radiation-induced death at relatively low doses in large mammals.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Gabriel S. PhD, Alexandria R. BS, Paul C. PhD, Liyong PhD, Ann R. DSc,