Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8222137 | International Journal of Radiation Oncology*Biology*Physics | 2013 | 5 Pages |
Abstract
Daily oral everolimus (10 mg) combined with both concurrent radiation and temozolomide followed by adjuvant temozolomide is well tolerated, with an acceptable toxicity profile. A randomized phase 2 clinical trial with mandatory correlative biomarker analysis is currently under way, designed to both determine the efficacy of this regimen and identify molecular determinants of response.
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Authors
Prakash MD, Minhee MA, Patrick Y. MD, Amyn M. MD, PhD, Merideth MD, Thomas A. MD, Benjamin W. MD, Minesh P. MD, FASTRO,