Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8222345 | International Journal of Radiation Oncology*Biology*Physics | 2013 | 8 Pages |
Abstract
Vasculogenesis is a major mechanism for tumor vessel survival during F-RT. Complex interactions occur between vessel-targeting agents and F-RT, and a synergistic effect may not always exist. To enhance F-RT, using CXCR4 inhibitor to block BM cell influx and the vasculogenesis process is a better strategy than targeting pericytes by epidermal growth factor receptor inhibitor.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Fang-Hsin PhD, Sheng-Yung BSc, Ying-Chieh MD, Chun-Chieh MD, PhD, Chi-Shiun PhD, Ji-Hong MD, PhD,