| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8222706 | International Journal of Radiation Oncology*Biology*Physics | 2013 | 7 Pages |
Abstract
Targeted Hedgehog pathway inhibition can increase in vivo radiation efficacy in lung cancer preclinical models. This effect is associated with pathway suppression in tumor-associated stroma. These data support clinical testing of Hedgehog inhibitors as a component of multimodality therapy for locally advanced non-small cell lung cancer.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Jing MD, Khaled BS, Sivarajan T. PhD, Blake T. PhD, Michael BS, Rajendra PhD, Nishant MS, Tarek BS, Joseph M. MD, John PhD, Charles M. MD, PhD, Phuoc T. MD, PhD, Russell K. MD,