Article ID Journal Published Year Pages File Type
8223458 International Journal of Radiation Oncology*Biology*Physics 2013 5 Pages PDF
Abstract
Celecoxib significantly reduced lung toxicity when administered months after LTI when the deleterious effects of radiation were expressed. The schedule-dependent reduction in fatal pneumonitis suggests that celecoxib could be clinically useful by reintroduction of treatment months after completion of radiation therapy. These findings may be important for designing clinical trials using cyclooxygenase-2 inhibitors to treat radiation-induced lung toxicity as a complement to concurrent radiation therapy of lung cancers.
Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Authors
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